Neurology Evidence by unknow
Author:unknow
Language: eng
Format: epub
Publisher: Wolters Kluwer
Published: 2017-08-15T00:00:00+00:00
BACKGROUND
The incidence of cryptococcal meningitis (CM) markedly increased as a result of HIV, particularly in developing countries. At the time of this publication, the ideal management of CM remained unclear. Amphotericin B (AmB) and flucytosine had not been shown to reduce mortality as compared to AmB monotherapy, and flucytosine was often not available in areas of the world where disease burden was greatest. Due to greater availability of fluconazole, fluconazole and not flucytosine was part of the treatment regimen for some patients based on their geography.
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